comfortability.

In life we all come in contact with things that make us uncomfortable (such as people, movies, situations, etc...) but do we still pursue those things in order for comfortability or is there a line you draw? If one thing is comfortable to someone else and not to you, do you continue in order to be fair with the other person, or should they not in order to not make you uncomfortable? What do you do when all your friends are comfortable with something, and you aren't? Are there things that take time to get use to, or take doing over and over to get comfortable with? Where is the line drawn? When should you be okay with being uncomfortable and not?